A-GPC is an important dietary source of choline, one of the key neurotransmitters for brain and memory function. Studies have also explored A-GPC’s (alpha-glycerylphosphorylcholine) ability to influence reaction time in humans, including reaction times related to physical performance.1 While some studies have looked at A-GPC’s influence on endurance, a new study2 suggests that A-GPC supplementation may directly improve lower-body muscle strength.
Published in the Journal of the International Society of Sports Nutrition, the double-blind, placebo-controlled crossover study administered 600 mg daily of Chemi Nutra’s (Austin, TX) AlphaSize A-GPC ingredient for six days to 13 college-age males. Following supplementation, the subjects underwent lower- and upper-body strength tests. For lower-body testing, they participated in an isometric mid-thigh pull test. For upper-body testing, they performed push-up–type tests against a high-frequency load cell. 